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Products  >  Human-Field  >  Helicobacter pylori  >  Science



• Intestinal parasites, growth and physical fitness of schoolchildren in poor neighbourhoods of Port Elizabeth, South Africa: a cross-sectional survey.

Müller I, Yap P, Steinmann P, Damons BP, Schindler C, Seelig H, Htun NS, Probst-Hensch N, Gerber M, du Randt R, Pühse U, Walter C, Utzinger J

Parasit Vectors. 2016 Sep 5;9(1):488.


As traditional lifestyle and diets change with social and economic development, disadvantaged communities in low- and middle-income countries increasingly face a double burden of communicable and non-communicable diseases. We studied the relationship between physical fitness and infections with soil-transmitted helminths (STHs), intestinal protozoa and Helicobacter pylori among schoolchildren in Port Elizabeth, South Africa.


We conducted a cross-sectional survey among 1009 children, aged 9 to 12 years, from eight primary schools in socioeconomically disadvantaged neighbourhoods of Port Elizabeth. Physical fitness was determined using field-deployable tests of the Eurofit fitness test battery. Stool samples were analysed with the Kato-Katz thick smear technique to diagnose STHs and with rapid diagnostic tests (RDTs) to detect intestinal protozoa and H. pylori infections. Haemoglobin (Hb) levels were assessed and anthropometric indicators determined.


Complete data were available for 934 children (92 %). In two schools, high STH prevalences were found (Ascaris lumbricoides 60 and 72 %; Trichuris trichiura 65 % each). For boys and girls co-infected with A. lumbricoides and T. trichiura (n = 155) the maximal oxygen uptake (VO2 max) was estimated to be 50.1 and 47.2 ml kg(-1) min(-1), compared to 51.5 and 47.4 ml kg(-1) min(-1) for their non-infected peers (n = 278), respectively. On average, children without helminth infections had greater body mass (P = 0.011), height (P = 0.009) and a higher body mass index (P = 0.024) and were less often stunted (P = 0.006), but not significantly less wasted compared to their peers with a single or dual species infection. Among 9-year-old boys, a negative correlation between helminth infections and VO2 max, grip strength and standing broad jump distance was observed (P = 0.038). The overall mean Hb level was 122.2 g l(-1). In the two schools with the highest prevalence of STHs the Hb means were 119.7 and 120.5 g l(-1), respectively.


Intestinal parasite infections appear to have a small but significant negative effect on the physical fitness of infected children, as expressed by their maximal oxygen uptake. We observed a clear impact on anthropometric indicators.


• Diagnosis of Helicobacter pylori infection in Indonesian children: comparison of Helicobacter pylori Stool Antigen with Enzyme-Immunoassay and a new Rapid Test.

Prasetyo D, Gerritsen HJ, Mertens P, Labrune V, Leclipteux T and Kuijper E.J

19th European Congress of Clinical Microbiology and Infectious Diseases  16-19 May, 2009.

Diagnosis of Helicobacter pylori infection


• Comparison of Enzyme-Immunoassay and a new membrane Rapid Test for detecting Helicobacter pylori Stool Antigen

Prasetyo D, Gerritsen HJ, Mertens P, Labrune V, Leclipteux T and Kuijper E.J

Dutch Society of Medical Microbiology - Scientific Spring Meeting 2009

Detection of Helicobacter pylori in stool


• Evaluation of the Pylori-Strip kit to diagnose the H. Pylori antigens in fecal material.

Ortiz D, Cavazza ME

September 2009

Evaluation of PyloriStrip


• 7th Conference on New Frontiers in Microbiology and Infection: Helicobacter pylori from basic research to clinical issues, Geneva, Switzerland,

The diagnosis and genetic determination of H. pylori infection in adult dyspeptic patients in a tertiary care hospital of Pakistan.

Dr. Ali Khalid

October 2011


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